By Riekelt H. Houtkooper (eds.)
The sirtuin kin of proteins (SIRT1-7) obtained loads of cognizance in recent times as they function metabolic sensors that regulate not just metabolism, but additionally getting older and lifespan legislation. As such, sirtuins are robust objectives for the remedy of age-related metabolic ailments, together with weight problems, diabetes, and melanoma. certainly, many study teams in addition to pharmaceutical businesses chanced on nutrition parts and/or medicinal drugs that focus on the sirtuins and supply major future health advantages. This e-book specializes in a variety of facets of sirtuin biology, from simple biochemistry, through molecular functionality, to its function in (fighting) human disease.