By Charles S. Cleeland, Michael J. Fisch, Adrian J. Dunn
Melanoma Symptom technology is the 1st interdisciplinary compilation of analysis at the mechanisms underlying the expression of cancer-related indicators. It offers thoughts in scientific, animal and in vitro study, study equipment in mind imaging, and statistical-descriptive ways to figuring out the mechanistic foundation of symptom expression. This quantity additionally presents views from sufferers, govt and undefined. by means of gathering and synthesizing the constructing threads of latest ways to knowing cancer-related indicators, the e-book promotes a pioneering framework for merging behavioral and organic disciplines to elucidate mechanisms of symptom evolution, incorporating new applied sciences, checking out novel brokers for symptom keep watch over, and enhancing sufferer functioning and caliber of existence either in the course of and after melanoma remedy. With a professional editorial crew led through Charles S. Cleeland, an internationally-recognized chief in melanoma soreness overview and remedy, this can be crucial examining for surgical, medical and scientific oncologists, educational researchers, and pharmaceutical businesses constructing new brokers to manage symptom expression
Preface; Foreword; half I. advent: 1. advent to melanoma Symptom technological know-how Charles S. Cleeland, Adrian J. Dunn and Michael J. Fisch; 2. getting to know the mechanisms underlying the indicators of sufferers with melanoma Adrian J. Dunn; three. Cytokines, illness habit: a version for melanoma indicators Steven S. Zalcman, Randall T. Woodruff, Ruchika Mohla and Allan Siegal; half II. melanoma Symptom Mechanisms and versions: scientific and uncomplicated technological know-how: four. The medical technology of melanoma soreness overview and administration Russell okay. Portenoy and Victor T. Chang; five. soreness: uncomplicated technological know-how: 5a. Mechanisms of disease-related ache in melanoma: insights from the learn of bone tumors Patrick W. Mantyh and Juan Miguel Jimenez Andrade; 5b. Neuropathic soreness: easy technological know-how Patrick M. Dougherty and Haijun Zhang; 6. Cognitive disorder: is chemobrain genuine? Christina A. Meyers and Jeffrey S. Wefel; 7. Cognitive impairment: easy technology Perry N. Fuchs, Jessica A. Boyette-Davis and Adrian J. Dunn; eight. melancholy in melanoma: pathophysiology on the mind-body interface Andrew H. Miller, Michael A. Burke and Charles L. Raison; nine. Depressive disease: uncomplicated technology: 9a. Animal versions of depressed temper and disorder habit Adrian J. Dunn; 9b. From irritation to ailment and melancholy: the cytokine connection Robert Dantzer and Keith W. Kelly; 10. Cancer-related fatigue: medical technology Xin Shelley Wang; eleven. constructing translational animal types of cancer-related fatigue Mary W. Meagher; 12. melanoma anorexia/weight loss syndrome Aminah Jatoi and Nisha Lassi; thirteen. urge for food loss/cachexia: uncomplicated technology Tristin D. Brisbois-Clarkson, Wendy V. Wismer and Vickie E. Baracos; 14. Sleep and its problems: scientific technological know-how Sofia Ancoli-Israel and Lianqi Liu; 15. Sleep and its issues Mark R. Opp and Luca Imeri; sixteen. Proteins and signs Bang-Ning Lee and James M. Reuben; 17. Genetic ways to treating and combating signs in sufferers with melanoma Quiling Shi and Charles S. Cleeland; 18. sensible imaging of signs T. Dorina Papageorgiou, Edward F. Jackson and Javier O. Valenzuela; 19. High-dose treatment and posttransplantation symptom burden: amazing a stability Sergio A. Giralt and Loretta A. Williams; half III. scientific views in Symptom administration and study: 20. selling symptom learn in cooperative teams Lynne I. Wagner and David Cella; 21. useful points of symptom administration in sufferers with melanoma Richard T. Lee and Michael J. Fisch; half IV. Symptom size: 22. Symptom size by means of sufferer document Charles S. Cleeland and Tito R. Mendoza; 23. The economics of cancer-related indicators: valuing supportive care interventions Lesley-Ann Miller and Jane C. Weeks; 24. Longitudinal types for indicators Diane L. Fairclough; 25. Bayesian adaptive layout: a brand new method of attempt the effectiveness of symptom-reducing brokers utilizing patient-reported results Valen E. Johnson and Tito R. Mendoza; half V. govt and views: 26. selling melanoma symptom technology study Ann O'Mara and Maria Sgambati; 27. constructing symptom administration medicines Joanna M. Brell and Lori M. Minasian; 28. Cancer-related indicators: concerns for attention in drug and healing organic product label claims within the usa Jane A. Scott; 29. Symptom learn: taking a look forward Charles S. Cleeland, Adrian J. Dunn and Michael J. Fisch; Index
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Brain Res 711(1–2):163–174, 1996. 24. Asarian L, Langhans W. Current perspectives on behavioural and cellular mechanisms of illness anorexia. Int Rev Psychiatry 17(6):451–459, 2005. Chapter 3 – Cytokines and sickness behavior 25. Merali Z, Brennan K, Brau P, Anisman H. Dissociating anorexia and anhedonia elicited by interleukin-1beta: antidepressant and gender effects on responding for “free chow” and “earned” sucrose intake. Psychopharmacology (Berl) 165(4):413–418, 2003. 26. Plata-Salamán CR.
Understanding the receptors and channels that subserve nociceptive processing, and the neurochemistry involved at each, will lead to more sophisticated classification of inferred mechanisms for pain. Similarly, understanding the types of perturbations in these systems that may underlie specific types of injury or be associated with specific types of subjective and objective phenomena may allow subclassification of both nociceptive and neuropathic pains. The inflammatory skin and bone pain models (presented in Chapter 5) exemplify this type of modeling.